Methyl Methacrylate → Retinol Palmitate

HRID 1174427Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1174427
[CH3:1][C:2]1[CH2:7][CH2:6][CH2:5][C:4]([CH3:9])([CH3:8])[C:3]=1/[CH:10]=[CH:11]/[C:12](/[CH3:21])=[CH:13]/[CH:14]=[CH:15]/[C:16](/[CH3:20])=[CH:17]/[CH2:18][OH:19].[CH3:22][C:23]([C:25]([O:27]C)=O)=C>O.C(OCC)(=O)C>[CH3:18][CH2:17][CH2:16][CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10][CH2:3][CH2:2][CH2:7][CH2:6][CH2:22][CH2:23][C:25]([O:19][CH2:18]/[CH:17]=[C:16](/[CH:15]=[CH:14]/[CH:13]=[C:12](/[CH:11]=[CH:10]/[C:3]1[C:4]([CH3:8])([CH3:9])[CH2:5][CH2:6][CH2:7][C:2]=1[CH3:1])\[CH3:21])\[CH3:20])=[O:27]

Komponenten

5

Edukt 2

HCID 6658Methyl MethacrylateHCID 445354Retinol

Produkt 1

HCID 5280531Retinol Palmitate

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 962WaterLösungsmittel2×HCID 8857Ethyl AcetateLösungsmittel2×

Versuchsvorschrift

An aqueous phase was prepared by dissolving 0.5 g of poly (vinyl alcohol) in 50 ml water saturated by 6 ml of ethyl acetate. An organic phase was prepared by dissolving 0.075 g Retinol Palmitate, 0.1 g mineral oil, 0.01 g of an antioxidant (chosen from BHA, BHT, tocopherol or their mixture) and 0.815 g PMMA in 5 ml of ethyl acetate. The organic phase was poured into the aqueous phase while stirring and then 100 ml of fresh water were added. The microcapsules formed were filtered, washed by water and dried at the temperature no higher 20° C. An average diameter of the microcapsules was 40 μm.

Aufarbeitung

  1. customAn aqueous phase was prepared
  2. customAn organic phase was prepared
  3. additionThe organic phase was poured into the aqueous phase
  4. customThe microcapsules formed
  5. filtrationwere filtered
  6. washwashed by water
  7. customdried at the temperature no higher 20° C

Quellen und Nachweise

ORD-Eintrag
ord-44664d50bbee4cd3992b24b085a78fc8
Quelldatensatz
uspto-grants-2010_11
Patentnummer
US07838037B2

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