4-Nitrobenzaldehyde → HCID 23135184, compound

HRID 1176191Notes

Reaction equation

HRID 1176191 reaction equation
C([O-])(=O)C.[NH4+:5].[C:6]([CH2:8][C:9]([O:11]C)=O)#[N:7].[CH:13]1([C:16](=O)[CH3:17])[CH2:15][CH2:14]1.[N+:19]([C:22]1[CH:29]=[CH:28][C:25]([CH:26]=O)=[CH:24][CH:23]=1)([O-:21])=[O:20]>>[CH:13]1([C:16]2[NH:5][C:9](=[O:11])[C:8]([C:6]#[N:7])=[C:26]([C:25]3[CH:28]=[CH:29][C:22]([N+:19]([O-:21])=[O:20])=[CH:23][CH:24]=3)[CH:17]=2)[CH2:15][CH2:14]1

Participants

5

Reactant 4

HCID 5414-NitrobenzaldehydeHCID 7747Methyl cyanoacetateHCID 13004Cyclopropyl methyl ketoneHCID 517165Ammonium Acetate

Product 1

HCID 23135184HCID 23135184, compound

Procedure

In analogy to the procedure described for Example 3a, reaction of 17.9 g ammonium acetate, 3.5 ml methyl cyanoacetate, 3.8 ml 1-cyclopropyl-ethanone, and 5 g 4-nitrobenzaldehyde yielded 3.23 g product.

Sources & evidence

ORD record
ord-4cf1152fe9d64289a6c4e2e83c28374a
Source dataset
uspto-grants-2010_11
Patent number
US07842809B2

Reaction notes

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