Dimethylformamide → 1-Methylethyl 4-[({6-[4-(1-pyrrolidinylcarbonyl)phenyl]-3-pyridinyl}oxy)methyl]-1-piperidinecarboxylate

HRID 118170Notes

Reaction equation

HRID 118170 reaction equation
[CH2:30]1[CH2:31][CH2:32][NH:33][CH2:34]1.[CH3:1][CH:2]([CH3:3])[O:4][C:5](=[O:6])[N:7]1[CH2:8][CH2:9][CH:10]([CH2:13][O:14][c:15]2[cH:16][cH:17][c:18](-[c:21]3[cH:22][cH:23][c:24]([C:25](=[O:26])[OH:27])[cH:28][cH:29]3)[n:19][cH:20]2)[CH2:11][CH2:12]1.[CH:59]([N:60]([CH:61]([CH3:62])[CH3:63])[CH2:64][CH3:65])([CH3:66])[CH3:67].[O:68]=[CH:69][N:70]([CH3:71])[CH3:72].[P-:35]([F:36])([F:37])([F:38])([F:39])([F:40])[F:41].[n:42]1([O:43][C:44]([N:45]([CH3:46])[CH3:47])=[N+:48]([CH3:49])[CH3:50])[c:51]2[n:52][cH:53][cH:54][cH:55][c:56]2[n:57][n:58]1>>[CH3:1][CH:2]([CH3:3])[O:4][C:5](=[O:6])[N:7]1[CH2:8][CH2:9][CH:10]([CH2:13][O:14][c:15]2[cH:16][cH:17][c:18](-[c:21]3[cH:22][cH:23][c:24]([C:25](=[O:27])[N:33]4[CH2:32][CH2:31][CH2:30][CH2:34]4)[cH:28][cH:29]3)[n:19][cH:20]2)[CH2:11][CH2:12]1

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 9886HexafluorophosphateHCID 31268PyrrolidineHCID 81531DiisopropylethylamineHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 66673118HCID 66673118, compound

Product 1

HCID 249965531-Methylethyl 4-[({6-[4-(1-pyrrolidinylcarbonyl)phenyl]-3-pyridinyl}oxy)methyl]-1-piperidinecarboxylate

Sources & evidence

ORD record
ord-8c7b454e490247ed93d9321bd10fe200
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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