Dimethyl Sulfide → HCID 178439422, compound

HRID 1182435Notes

Reaction equation

HRID 1182435 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:11]=[C:12]([Cl:26])[C:13]=1[O:14][C:15]1[CH:20]=[CH:19][C:18]([O:21]C)=[C:17]([CH:23]([CH3:25])[CH3:24])[CH:16]=1)[CH2:5][C:6]1[NH:10][N:9]=[N:8][N:7]=1.B(F)(F)F.S(C)C>C(Cl)Cl>[Cl:1][C:2]1[CH:3]=[C:4]([CH:11]=[C:12]([Cl:26])[C:13]=1[O:14][C:15]1[CH:20]=[CH:19][C:18]([OH:21])=[C:17]([CH:23]([CH3:24])[CH3:25])[CH:16]=1)[CH2:5][C:6]1[NH:10][N:9]=[N:8][N:7]=1

Participants

5

Reactant 3

HCID 1068Dimethyl SulfideHCID 6356Boron trifluorideHCID 178492477HCID 178492477, compound

Product 1

HCID 178439422HCID 178439422, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A reaction mixture of 3,5-dichloro-4-(4-methoxy-3-isopropylphenoxy)-benzyltetrazole (60 mg), BF3.Me2S (0.5 ml) and CH2Cl2 (6 ml) was stirred at room temperature over night. The yield after purification was quantitative.

Workup

  1. customThe yield
  2. customafter purification

Sources & evidence

ORD record
ord-c760587af0a9433796156797d7a55326
Source dataset
uspto-grants-2007_10
Patent number
US07288571B2

Reaction notes

Loading…