Sodium Bisulfate → HCID 67124545, compound

HRID 1184414Notes

Reaction equation

HRID 1184414 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([C@@H:8]2[CH2:13][C:12](=[O:14])[CH2:11][CH2:10][C@H:9]2[C:15]([O-:17])=[O:16])=[CH:4][CH:3]=1.C1([NH2+]C2CCCCC2)CCCCC1.OS([O-])(=O)=O.[Na+]>CCOC(C)=O>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([C@@H:8]2[CH2:13][C:12](=[O:14])[CH2:11][CH2:10][C@H:9]2[C:15]([OH:17])=[O:16])=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 516919Sodium BisulfateHCID 86692736HCID 86692736, compound

Product 1

HCID 67124545HCID 67124545, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

A suspension of the product from step C (5 g, 10.46 mmol) in EtOAc (100 mL) was treated with 1M aq NaHSO4 (100 mL) at rt. The biphasic mixture was stirred for 12 h at rt and then separated. The organic layer was washed with water and brine, dried (Na2SO4), filtered and concentrated to afford the title compound. HPLC/MS: 297.0/299.0 (M+1); Rt=2.55 min.

Workup

  1. customseparated
  2. washThe organic layer was washed with water and brine
  3. dry with materialdried (Na2SO4)
  4. filtrationfiltered
  5. concentrationconcentrated

Sources & evidence

ORD record
ord-97cf593752b84c3d832f51155bbe8f58
Source dataset
uspto-grants-2014_03
Patent number
US08669252B2

Reaction notes

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