反应详情

To a solution of 4.63 g (S)-4-(4-benzyl-2H-tetrazol-5-yl)-2-tert-butoxycarbonylamino-butyric acid benzyl ester in 400 ml ethyl acetate were added 800 mg Pd(OH)2/C (10%) and the suspension stirred under an atmosphere of hydrogen (4 bar) for 12 h. The reaction mixture was filtrated over a plug of Celite® and washed with ethyl acetate. Yield: 2.84 g colorless solid.

1. filtrationThe reaction mixture was filtrated over a plug of Celite®
2. washwashed with ethyl acetate