Hydrochloric Acid → HCID 86666484, compound

HRID 1189681Notes

Reaction equation

HRID 1189681 reaction equation
[CH3:1][NH2:2].[F:3][C:4]1[C:12]([F:13])=[C:11](F)[C:10]([N+:15]([O-:17])=[O:16])=[CH:9][C:5]=1[C:6]([OH:8])=[O:7].Cl>O>[F:3][C:4]1[C:12]([F:13])=[C:11]([NH:2][CH3:1])[C:10]([N+:15]([O-:17])=[O:16])=[CH:9][C:5]=1[C:6]([OH:8])=[O:7]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 6329MethylamineHCID 158712412,3,4-Trifluoro-5-nitrobenzoic acid

Product 1

HCID 86666484HCID 86666484, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of methylamine (40% aq solution, 0.68 mL, 6.7 mmol), 2,3,4-trifluoro-5-nitro-benzoic acid (0.50 g, 2.3 mmol) and 5 mL water is stirred for 3 h in an ice bath. Then the mixture is acidified with 6M aq HCl and the resulting precipitate is collected by filtration washed with water and dried.

Workup

  1. filtrationthe resulting precipitate is collected by filtration
  2. washwashed with water
  3. customdried

Sources & evidence

ORD record
ord-4277a82d07a84988a2078956ec654e85
Source dataset
uspto-grants-2014_03
Patent number
US08674113B2

Reaction notes

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