反应详情

The sub-title compound is prepared in analogy to 6a from N-(3,3,3-trifluoro-propyl)-2-chloro-4-methylamino-5-nitro-benzoic acid amide (compound 81a; 2.0 g, 6.5 mmol), 4-trifluormethyl-piperidine×HCl (2.45 g, 13 mmol), DIPEA (4.9 mL, 29 mmol) and MeCN (25 mL) in a pressure flask at 80° C.