2-Amino-2-methyl-1,3-propanediol → HCID 131731253, compound

HRID 1190789Notes

Reaction equation

[CH3:1][CH2:2][CH2:3][CH2:4][O:5][P:6]([O:13][CH2:14][CH2:15][CH2:16][CH3:17])([O:8][CH2:9][CH2:10][CH2:11][CH3:12])=[O:7].[CH3:18][C:19]([NH2:24])([CH2:22][OH:23])[CH2:20][OH:21]>>[CH3:12][CH2:11][CH2:10][CH2:9][O:8][P:6]([O:5][CH2:4][CH2:3][CH2:2][CH3:1])([O:13][CH2:14][CH2:15][CH2:16][CH3:17])=[O:7].[CH3:18][C:19]([NH2:24])([CH2:22][OH:23])[CH2:20][OH:21]

Participants

Reactant 2

HCID 15312-Amino-2-methyl-1,3-propanediol

HCID 31357Tributyl Phosphate

Product 1

HCID 131731253HCID 131731253, compound

Procedure

Reaction of TBPA with AMPD gives an TBPA/AMPD adduct. AMPD is sold in commerce by Angus. 37.2 mmol of TBPA was combined with 37.2 mmol of AMPD in 164.5 g of pure ethanol. The mixture is refluxed for 2 hours. The solvent was removed using a rotary evaporator to produce a white solid.

Sources & evidence

ORD record: ord-50741cdd210a4d198527218adf03e46c
Source dataset: uspto-grants-2014_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08679990B2

Reaction notes

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