Diethanolamine → HCID 1925938, compound

HRID 1192764Notes

Reaction equation

HRID 1192764 reaction equation
CO[C:3](=[O:8])[C:4]([F:7])([F:6])[F:5].[NH:9]([CH2:13][CH2:14][OH:15])[CH2:10][CH2:11][OH:12]>C1COCC1>[F:7][C:4]([F:5])([F:6])[C:3]([N:9]([CH2:13][CH2:14][OH:15])[CH2:10][CH2:11][OH:12])=[O:8]

Participants

4

Reactant 2

HCID 8113DiethanolamineHCID 9893Methyl trifluoroacetate

Product 1

HCID 1925938HCID 1925938, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Methyltrifluoroacetate (25 g, 195.3 mmol) was added drop wise to an ice cooled stirred solution of 2,2′-iminodiethanol (20.5 g, 195 mmol) in anhydrous THF (100 mL). The reaction mixture was allowed to warm to ambient temperature naturally and stirred over night at ambient temperature. The solvent was evaporated via rotary evaporation to yield the title compound as a clear oil.

Workup

  1. temperaturecooled
  2. customThe solvent was evaporated via rotary evaporation

Sources & evidence

ORD record
ord-a294d5e640094ab5a0db92bad97bbbaa
Source dataset
uspto-grants-2014_03
Patent number
US08680273B2

Reaction notes

Loading…