Hydrazine hydrate (1:1) → HCID 13592806, compound

HRID 1194666Notes

Reaction equation

HRID 1194666 reaction equation
[O:1]=[C:2]1[NH:6][CH2:5][CH2:4][N:3]1[C:7]1[CH:12]=[CH:11][C:10]([C:13](=O)[CH:14]([CH3:19])[CH2:15][C:16](O)=[O:17])=[CH:9][CH:8]=1.O.[NH2:22][NH2:23]>C(O)C.CN(C)C=O>[O:1]=[C:2]1[NH:6][CH2:5][CH2:4][N:3]1[C:7]1[CH:12]=[CH:11][C:10]([C:13]2[CH:14]([CH3:19])[CH2:15][C:16](=[O:17])[NH:22][N:23]=2)=[CH:9][CH:8]=1

Participants

5

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 13592805HCID 13592805, compound

Product 1

HCID 13592806HCID 13592806, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolventHCID 6228DimethylformamideSolvent

Procedure

4 g (0.014 mole) of the compound prepared in Example 4 are stirred with 1 ml (0.021 mole) of hydrazine hydrate in 30 ml of ethanol and 20 ml of dimethylformamide at 80° C. for 2 hours. After the mixture has been cooled, the product is filtered off with suction and recrystallised from dimethylformamide.

Workup

  1. temperatureAfter the mixture has been cooled
  2. filtrationthe product is filtered off with suction
  3. customrecrystallised from dimethylformamide

Sources & evidence

ORD record
ord-78291319fe5747ccb845a78b046360aa
Source dataset
uspto-grants-1989_03
Patent number
US04816454

Reaction notes

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