1,2-Dichloroethane → N-[4-(Benzyloxy)phenyl]-7-fluoro-6-[5-({[2-(methanesulphonyl)ethyl]amino}methyl)-2-furyl]-4-quinazolinamine
Reaction equation
[C:51]([O:52][BH-:53]([O:54][C:55](=[O:56])[CH3:57])[O:58][C:59](=[O:60])[CH3:61])(=[O:62])[CH3:63].[CH2:2]([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[O:9][c:10]1[cH:11][cH:12][c:13]([NH:16][c:17]2[n:18][cH:19][n:20][c:21]3[cH:22][c:23]([F:34])[c:24](-[c:27]4[cH:28][cH:29][c:30]([CH:32]=[O:33])[o:31]4)[cH:25][c:26]23)[cH:14][cH:15]1.[CH3:44][S:45](=[O:46])(=[O:47])[CH2:48][CH2:49][NH2:50].[CH3:69][C:70](=[O:71])[OH:72].[CH:35]([N:36]([CH:37]([CH3:38])[CH3:39])[CH2:40][CH3:41])([CH3:42])[CH3:43].[Cl:65][CH2:66][CH2:67][Cl:68].[ClH:1].[Na+:64]>>[CH2:2]([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[O:9][c:10]1[cH:11][cH:12][c:13]([NH:16][c:17]2[n:18][cH:19][n:20][c:21]3[cH:22][c:23]([F:34])[c:24](-[c:27]4[cH:28][cH:29][c:30]([CH2:32][NH:50][CH2:49][CH2:48][S:45]([CH3:44])(=[O:46])=[O:47])[o:31]4)[cH:25][c:26]23)[cH:14][cH:15]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-d22ec2b8cb714638bf666c479588c715
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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