反应详情

The compound of Step A (7.2 g) was added to a suspension of tin (II) chloride (28 g) in ethanol (45 ml). The mixture was refluxed for 1.5 h. The reaction was diluted with ethyl acetate and neutralized by careful addition of saturated sodium bicarbonate solution. The organic solution was washed with brine and the solvent was dried over magnesium sulfate. Evaporation of the solution left a thick oil of the title compound (5.8 g).

1. temperatureThe mixture was refluxed for 1.5 h
2. washThe organic solution was washed with brine
3. dry with materialthe solvent was dried over magnesium sulfate
4. customEvaporation of the solution
5. waitleft a thick oil of the title compound (5.8 g)