反应详情

The title compound was prepared from 2',4'-difluoroacetophenone (5.0 g, 0.032 mol), octyl isocyanate (4.97 g, 0.032 mol), and lithium diisopropylamide (0.032 mol) using the procedure described in Example 1. Purification by flash chromatography (silica gel, 20% EtoAc/hexane) yielded 4.25 g (0.013 mol, 42.6%) of the desired product.

1. customPurification by flash chromatography (silica gel, 20% EtoAc/hexane)