m-Chloroperbenzoic acid → HCID 15059459, compound

HRID 1199456Notes

Reaction equation

HRID 1199456 reaction equation
COC1C=CC2N[C:8]([S:10]([C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=3[C:18]3[CH:23]=[C:22]([O:24][CH3:25])[CH:21]=[CH:20][N:19]=3)=[O:11])=NC=2C=1.ClC1C=CC=C(C(OO)=O)C=1>C(OCC)(=O)C>[CH3:25][O:24][C:22]1[CH:21]=[CH:20][N:19]=[C:18]([C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=2[S:10]([CH3:8])=[O:11])[CH:23]=1

Participants

4

Reactant 2

HCID 70297m-Chloroperbenzoic acidHCID 178493115HCID 178493115, compound

Product 1

HCID 15059459HCID 15059459, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent2×

Procedure

The product of step (a) above (750 mg) in ethyl acetate (7 ml) was cooled to -10° and treated with a solution of m-Chloroperbenzoic acid (660 mg) in ethyl acetate (4 ml). After 1 hour the solution was washed with sodium bicarbonate solution, sodium bisulphate solution and brine then dried and evaporated. The residue was flash chromatographed (ethyl acetate) to produce the subtitle compound as a clear oil MS (FAB) M+1 at 248 bp 232.

Workup

  1. washAfter 1 hour the solution was washed with sodium bicarbonate solution, sodium bisulphate solution and brine
  2. customthen dried
  3. customevaporated
  4. customchromatographed (ethyl acetate)

Sources & evidence

ORD record
ord-9310b59cffc547e8b0f6125f6f5a8701
Source dataset
uspto-grants-1990_02
Patent number
US04900751

Reaction notes

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