Sodium ion → N-(4-thiophen-3-yl-phenyl)-acetamide

HRID 1200540Notes

Reaction equation

HRID 1200540 reaction equation
[Br:22][c:23]1[cH:24][cH:25][c:26]([NH:29][C:30]([CH3:31])=[O:32])[cH:27][cH:28]1.[CH3:1][c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1.[CH3:33][CH2:34][O:35][C:36](=[O:37])[CH3:38].[Na+:8].[Na+:9].[O-:10][C:11](=[O:12])[O-:13].[OH2:62].[Pd:58].[Pd:59].[Pd:60].[Pd:61].[c:39]1([P:40]([c:41]2[cH:42][cH:43][cH:44][cH:45][cH:46]2)[c:47]2[cH:48][cH:49][cH:50][cH:51][cH:52]2)[cH:53][cH:54][cH:55][cH:56][cH:57]1.[s:14]1[cH:15][c:16]([B:19]([OH:20])[OH:21])[cH:17][cH:18]1>>[s:14]1[cH:15][c:16](-[c:23]2[cH:24][cH:25][c:26]([NH:29][C:30]([CH3:31])=[O:32])[cH:27][cH:28]2)[cH:17][cH:18]1

Participants

10

Reactant 9

HCID 923Sodium ion2×HCID 962WaterHCID 1140TolueneHCID 76834'-BromoacetanilideHCID 8857Ethyl AcetateHCID 11776TriphenylphosphineHCID 19660Carbonate IonHCID 23938Palladium4×HCID 581760Thiophene-3-boronic acid

Product 1

HCID 57875827N-(4-thiophen-3-yl-phenyl)-acetamide

Sources & evidence

ORD record
ord-5afab9b3c3fb4e9f999e0c46d14230b1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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