Ammonium → ethyl 5,6-dihydro-11-chloro-4H-azocino[3,2,1-hi]indole-2-carboxylate

HRID 1200946Notes

Reaction equation

HRID 1200946 reaction equation
[CH3:22][CH2:23][N:24]([CH2:25][CH3:26])[CH2:27][CH3:28].[CH3:29][S:30](=[O:31])(=[O:32])[Cl:33].[Cl-:34].[Cl:1][c:2]1[c:3]2[cH:4][c:5]([C:17](=[O:18])[O:19][CH2:20][CH3:21])[n:6]3[c:7]2[c:8]([cH:9][cH:10]1)[CH:11]([OH:16])[CH2:12][CH2:13][CH2:14][CH2:15]3.[NH4+:35].[O:36]1[CH2:37][CH2:38][CH2:39][CH2:40]1>>[Cl:1][c:2]1[c:3]2[cH:4][c:5]([C:17](=[O:18])[O:19][CH2:20][CH3:21])[n:6]3[c:7]2[c:8]([cH:9][cH:10]1)[CH:11]=[CH:12][CH2:13][CH2:14][CH2:15]3

Participants

7

Reactant 6

HCID 223AmmoniumHCID 312ChlorideHCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 21714297ethyl 5,6,7,8-tetrahydro-11-chloro-8-hydroxy-4H-azocino [3,2,1-hi]indole-2-carboxylate

Product 1

HCID 70238243ethyl 5,6-dihydro-11-chloro-4H-azocino[3,2,1-hi]indole-2-carboxylate

Sources & evidence

ORD record
ord-01397f8f1e674edeb62fa8d8b7890452
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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