Tetrahydrofuran → tert-Butyl 4-((2-chloroquinazolin-4-yl)amino)piperidine-1-carboxylate
Reaction equation
[CH2:27]1[O:28][CH2:29][CH2:30][CH2:31]1.[CH3:32][N:33]([c:34]1[cH:35][cH:36][n:37][cH:38][cH:39]1)[CH3:40].[CH3:41][CH2:42][O:43][C:44]([CH3:45])=[O:46].[CH3:47][CH2:48][CH2:49][CH2:50][CH2:51][CH3:52].[Cl:1][c:2]1[n:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]2[c:10]([Cl:12])[n:11]1.[NH2:13][CH:14]1[CH2:15][CH2:16][N:17]([C:20](=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[CH2:18][CH2:19]1>>[Cl:1][c:2]1[n:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]2[c:10]([NH:13][CH:14]2[CH2:15][CH2:16][N:17]([C:20](=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[CH2:18][CH2:19]2)[n:11]1Participants
7
Sources & evidence
- ORD record
- ord-3775844bcf2c4e96b2e67e0cf614d070
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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