Dimethylformamide → 1-[(2-Methoxy-3-pyridyl)methyl]-4-[2-[3-(methylsulfonyl)-2-thienyl]-1-ethynyl]piperidine
Reaction equation
[Br:18][c:19]1[s:20][cH:21][cH:22][c:23]1[S:24](=[O:25])(=[O:26])[CH3:27].[CH3:113][CH2:114][O:115][C:116](=[O:117])[CH3:118].[CH3:119][N:120]([CH3:121])[CH:122]=[O:123].[CH3:1][O:2][c:3]1[n:4][cH:5][cH:6][cH:7][c:8]1[CH2:9][N:10]1[CH2:11][CH2:12][CH:13]([C:16]#[CH:17])[CH2:14][CH2:15]1.[CH3:29][CH2:30][N:31]([CH2:32][CH3:33])[CH2:34][CH3:35].[I-:28].[cH:36]1[cH:37][cH:38][c:39]([P:40]([Pd:41]([P:42]([c:43]2[cH:44][cH:45][cH:46][cH:47][cH:48]2)([c:49]2[cH:50][cH:51][cH:52][cH:53][cH:54]2)[c:55]2[cH:56][cH:57][cH:58][cH:59][cH:60]2)([P:61]([c:62]2[cH:63][cH:64][cH:65][cH:66][cH:67]2)([c:68]2[cH:69][cH:70][cH:71][cH:72][cH:73]2)[c:74]2[cH:75][cH:76][cH:77][cH:78][cH:79]2)[P:80]([c:81]2[cH:82][cH:83][cH:84][cH:85][cH:86]2)([c:87]2[cH:88][cH:89][cH:90][cH:91][cH:92]2)[c:93]2[cH:94][cH:95][cH:96][cH:97][cH:98]2)([c:99]2[cH:100][cH:101][cH:102][cH:103][cH:104]2)[c:105]2[cH:106][cH:107][cH:108][cH:109][cH:110]2)[cH:111][cH:112]1>>[CH3:1][O:2][c:3]1[n:4][cH:5][cH:6][cH:7][c:8]1[CH2:9][N:10]1[CH2:11][CH2:12][CH:13]([C:16]#[C:17][c:19]2[s:20][cH:21][cH:22][c:23]2[S:24](=[O:25])(=[O:26])[CH3:27])[CH2:14][CH2:15]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-bcd4e765d76348dfbd842557f1f172e4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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