Bromide ion → 5-Bromo-2-cyclopropylpyridine

HRID 1202460Notes

Reaction equation

HRID 1202460 reaction equation
[Br-:6].[Br:11][c:12]1[n:13][cH:14][c:15]([Br:18])[cH:16][cH:17]1.[C:19](=[O:20])([OH:21])[O-:22].[CH2:1]1[O:2][CH2:3][CH2:4][CH2:5]1.[CH:7]1([Mg+:10])[CH2:8][CH2:9]1.[Cl-:24].[Cl-:26].[Fe+2:66].[Na+:23].[Pd:27]([Cl:28])[Cl:29].[Zn+2:25].[cH:30]1[cH:31][cH:32][c:33]([P:34]([c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)[c-:41]2[cH:42][cH:43][cH:44][cH:45]2)[cH:46][cH:47]1.[cH:48]1[cH:49][cH:50][c:51]([P:52]([c:53]2[cH:54][cH:55][cH:56][cH:57][cH:58]2)[c-:59]2[cH:60][cH:61][cH:62][cH:63]2)[cH:64][cH:65]1>>[CH:7]1([c:12]2[n:13][cH:14][c:15]([Br:18])[cH:16][cH:17]2)[CH2:8][CH2:9]1

Participants

12

Reactant 11

HCID 259Bromide ionHCID 312Chloride2×HCID 769Bicarbonate IonHCID 923Sodium ionHCID 8028TetrahydrofuranHCID 24290Palladium ChlorideHCID 27284Ferrous cationHCID 32051Zinc(2+)HCID 693532,5-DibromopyridineHCID 178420532HCID 178420532, compound2×HCID 178507030HCID 178507030, compound

Product 1

HCID 223177225-Bromo-2-cyclopropylpyridine

Sources & evidence

ORD record
ord-1d826927f94d46fb9b9da7500e188644
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…