Potassium Cation → 4-Ethynyl-1-(4-methoxybenzyl)-1H-pyrazole

HRID 1203399Notes

Reaction equation

HRID 1203399 reaction equation
[CH3:16][Si:17]([CH3:18])([CH3:19])[C:20]#[CH:21].[CH3:22][OH:23].[CH3:29][CH2:30][N:31]([CH2:32][CH3:33])[CH2:34][CH3:35].[Cl:26][CH2:27][Cl:28].[Cu:36][I:37].[I:1][c:2]1[cH:3][n:4][n:5]([CH2:7][c:8]2[cH:9][cH:10][c:11]([O:14][CH3:15])[cH:12][cH:13]2)[cH:6]1.[K+:25].[OH-:24]>>[c:2]1([C:20]#[CH:21])[cH:3][n:4][n:5]([CH2:7][c:8]2[cH:9][cH:10][c:11]([O:14][CH3:15])[cH:12][cH:13]2)[cH:6]1

Participants

9

Reactant 8

HCID 813Potassium CationHCID 887MethanolHCID 961HydroxideHCID 6344DichloromethaneHCID 8471TriethylamineHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 66111TrimethylsilylacetyleneHCID 574219364-iodo-1-[(4-methoxyphenyl)methyl]-1H-pyrazole

Product 1

HCID 574219374-Ethynyl-1-(4-methoxybenzyl)-1H-pyrazole

Sources & evidence

ORD record
ord-a4a7962586c0438f9cadb9fa8cf2c988
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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