Bicarbonate Ion → 2-[1-(2-Tert-butyl-6-chloro-5-methyl-pyrimidin-4-yl)-piperidin-4-yl]-[1,8]naphthyridine
Reaction equation
[C:10]([CH3:11])([CH3:12])([CH3:13])[c:14]1[n:15][c:16]([Cl:22])[c:17]([CH3:21])[c:18]([Cl:20])[n:19]1.[C:49](=[O:50])([OH:51])[O-:52].[CH3:55][CH2:56][O:57][C:58](=[O:59])[CH3:60].[CH3:61][C:62]([N:63]([CH3:64])[CH3:65])=[O:66].[CH:1]([N:2]([CH:3]([CH3:4])[CH3:5])[CH2:6][CH3:7])([CH3:8])[CH3:9].[NH:23]1[CH2:24][CH2:25][CH:26]([c:29]2[n:30][c:31]3[n:32][cH:33][cH:34][cH:35][c:36]3[cH:37][cH:38]2)[CH2:27][CH2:28]1.[Na+:53].[OH2:54].[n:39]1[c:40]2[c:41]([cH:42][cH:43][cH:44][n:45]2)[cH:46][cH:47][cH:48]1>>[C:10]([CH3:11])([CH3:12])([CH3:13])[c:14]1[n:15][c:16]([N:23]2[CH2:24][CH2:25][CH:26]([c:29]3[n:30][c:31]4[n:32][cH:33][cH:34][cH:35][c:36]4[cH:37][cH:38]3)[CH2:27][CH2:28]2)[c:17]([CH3:21])[c:18]([Cl:20])[n:19]1Participants
10
Reactant 9
Product 1
Sources & evidence
- ORD record
- ord-4d20b6f300da4c7ab3ab44f64639ea71
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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