Ammonium → 6-methoxy-N-[5-chloro-7-(3-methoxyprop-1-ynyl)-1,3-benzodioxol-4-yl]-7-[3-(4-methylpiperazin-1-yl)propoxy]quinazolin-4-amine
Reaction equation
[CH3:1][Si:2]([N-:3][Si:4]([CH3:5])([CH3:6])[CH3:7])([CH3:8])[CH3:9].[Cl-:61].[Cl:16][c:17]1[n:18][cH:19][n:20][c:21]2[cH:22][c:23]([O:29][CH2:30][CH2:31][CH2:32][N:33]3[CH2:34][CH2:35][N:36]([CH3:39])[CH2:37][CH2:38]3)[c:24]([O:27][CH3:28])[cH:25][c:26]12.[Cl:40][c:41]1[c:42]([NH2:55])[c:43]2[c:44]([c:48]([C:50]#[C:51][CH2:52][O:53][CH3:54])[cH:49]1)[O:45][CH2:46][O:47]2.[NH4+:62].[Na+:10].[O:11]1[CH2:12][CH2:13][CH2:14][CH2:15]1.[O:56]=[CH:57][N:58]([CH3:59])[CH3:60]>>[c:17]1([NH:55][c:42]2[c:41]([Cl:40])[cH:49][c:48]([C:50]#[C:51][CH2:52][O:53][CH3:54])[c:44]3[c:43]2[O:47][CH2:46][O:45]3)[n:18][cH:19][n:20][c:21]2[cH:22][c:23]([O:29][CH2:30][CH2:31][CH2:32][N:33]3[CH2:34][CH2:35][N:36]([CH3:39])[CH2:37][CH2:38]3)[c:24]([O:27][CH3:28])[cH:25][c:26]12Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-cd84b3ee8290454e8637f02988c57972
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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