Dimethylformamide → 5-(3,5-dicyano-1,4-dihydro-2,6-dimethyl-4-pyridinyl)-N-[2-(dimethylamino)ethyl]-1H-indazole-3-carboxamide

HRID 1203929Notes

Reaction equation

HRID 1203929 reaction equation
[C:1](#[N:2])[C:3]1=[C:4]([CH3:24])[NH:5][C:6]([CH3:23])=[C:7]([C:21]#[N:22])[CH:8]1[c:9]1[cH:10][c:11]2[c:12]([C:18](=[O:19])[OH:20])[n:13][nH:14][c:15]2[cH:16][cH:17]1.[CH3:25][CH2:26][N:27]([CH2:28][CH3:29])[CH2:30][CH3:31].[CH3:56][N:57]([CH2:58][CH2:59][NH2:60])[CH3:61].[O:62]=[CH:63][N:64]([CH3:65])[CH3:66].[P-:32]([F:33])([F:34])([F:35])([F:36])([F:37])[F:38].[n:39]1([O:40][C:41]([N:42]([CH3:43])[CH3:44])=[N+:45]([CH3:46])[CH3:47])[c:48]2[n:49][cH:50][cH:51][cH:52][c:53]2[n:54][n:55]1>>[C:1](#[N:2])[C:3]1=[C:4]([CH3:24])[NH:5][C:6]([CH3:23])=[C:7]([C:21]#[N:22])[CH:8]1[c:9]1[cH:10][c:11]2[c:12]([C:18](=[O:20])[NH:60][CH2:59][CH2:58][N:57]([CH3:56])[CH3:61])[n:13][nH:14][c:15]2[cH:16][cH:17]1

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 8471TriethylamineHCID 9886HexafluorophosphateHCID 66053N,N-DimethylethylenediamineHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 249594695-(3,5-dicyano-1,4-dihydro-2,6-dimethyl-4-pyridinyl)-1H-indazole-3-carboxylic acid

Product 1

HCID 249598365-(3,5-dicyano-1,4-dihydro-2,6-dimethyl-4-pyridinyl)-N-[2-(dimethylamino)ethyl]-1H-indazole-3-carboxamide

Sources & evidence

ORD record
ord-363d377c6e8a430ab2eb109dce8a67e3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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