Hydrochloric Acid → Tert-butyl 3-bromo-5-(2,2,2-trifluoro-1-hydroxyethyl)benzoate
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[O:7][C:8]([CH3:9])([CH3:10])[CH3:11])[cH:12][c:13]([CH:15]=[O:16])[cH:14]1.[CH3:17][Si:18]([C:19]([F:20])([F:21])[F:22])([CH3:23])[CH3:24].[CH3:26][CH2:27][CH2:28][CH2:29][N+:30]([CH2:31][CH2:32][CH2:33][CH3:34])([CH2:35][CH2:36][CH2:37][CH3:38])[CH2:39][CH2:40][CH2:41][CH3:42].[CH3:49][O:50][C:51]([CH3:52])([CH3:53])[CH3:54].[ClH:43].[F-:25].[O:44]1[CH2:45][CH2:46][CH2:47][CH2:48]1>>[Br:1][c:2]1[cH:3][c:4]([C:5](=[O:6])[O:7][C:8]([CH3:9])([CH3:10])[CH3:11])[cH:12][c:13]([CH:15]([OH:16])[C:19]([F:20])([F:21])[F:22])[cH:14]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-91f8c022044c459db69b2d3918adcaf6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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