N-methyl-2-pyrrolidone → N-(2-hydroxy-2,2-diphenylethyl)-4-(2-(pyridine-2-ylamino)thiazol-5-ylthio)picolinamide
Reaction equation
[CH3:39][CH2:40][N:41]=[C:42]=[N:43][CH2:44][CH2:45][CH2:46][N:47]([CH3:48])[CH3:49].[CH3:69][N:70]1[CH2:71][CH2:72][CH2:73][C:74]1=[O:75].[CH:60]([N:61]([CH:62]([CH3:63])[CH3:64])[CH2:65][CH3:66])([CH3:67])[CH3:68].[NH2:23][CH2:24][C:25]([OH:26])([c:27]1[cH:28][cH:29][cH:30][cH:31][cH:32]1)[c:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1.[OH:50][n:51]1[c:52]2[c:53]([cH:54][cH:55][cH:56][cH:57]2)[n:58][n:59]1.[n:1]1[c:2]([NH:7][c:8]2[s:9][c:10]([S:13][c:14]3[cH:15][c:16]([C:20](=[O:21])[OH:22])[n:17][cH:18][cH:19]3)[cH:11][n:12]2)[cH:3][cH:4][cH:5][cH:6]1>>[n:1]1[c:2]([NH:7][c:8]2[s:9][c:10]([S:13][c:14]3[cH:15][c:16]([C:20](=[O:22])[NH:23][CH2:24][C:25]([OH:26])([c:27]4[cH:28][cH:29][cH:30][cH:31][cH:32]4)[c:33]4[cH:34][cH:35][cH:36][cH:37][cH:38]4)[n:17][cH:18][cH:19]3)[cH:11][n:12]2)[cH:3][cH:4][cH:5][cH:6]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-37700be1c3e6432cb45b5560003e88f2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…