Tetrahydrofuran → 2-(1-(3-(Trifluoromethyl)phenylsulfonyl)piperidin-4-yloxy)isoindoline-1,3-dione
Reaction equation
[F:13][C:14]([c:15]1[cH:16][c:17]([S:21](=[O:22])(=[O:23])[N:24]2[CH2:25][CH2:26][CH:27]([OH:30])[CH2:28][CH2:29]2)[cH:18][cH:19][cH:20]1)([F:31])[F:32].[O:1]=[C:2]([O:3][CH2:4][CH3:5])[N:6]=[N:7][C:8]([O:9][CH2:10][CH3:11])=[O:12].[O:64]1[CH2:65][CH2:66][CH2:67][CH2:68]1.[OH:33][N:34]1[C:35](=[O:44])[c:36]2[cH:37][cH:38][cH:39][cH:40][c:41]2[C:42]1=[O:43].[c:45]1([P:46]([c:47]2[cH:48][cH:49][cH:50][cH:51][cH:52]2)[c:53]2[cH:54][cH:55][cH:56][cH:57][cH:58]2)[cH:59][cH:60][cH:61][cH:62][cH:63]1>>[F:13][C:14]([c:15]1[cH:16][c:17]([S:21](=[O:22])(=[O:23])[N:24]2[CH2:25][CH2:26][CH:27]([O:30][N:34]3[C:35](=[O:44])[c:36]4[cH:37][cH:38][cH:39][cH:40][c:41]4[C:42]3=[O:43])[CH2:28][CH2:29]2)[cH:18][cH:19][cH:20]1)([F:31])[F:32]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-6afca1e786db438aa4408a524ed444fe
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…