Hydrochloric Acid → 13-cyclohexyl-N-(imidazo[1,2-a]pyridin-2-ylmethyl)-6-[[4-(4-morpholinyl)-1-piperidinyl]carbonyl]-7H-indolo[2,1-a][2]benzazepine-10-carboxamide

HRID 1208341Notes

Reaction equation

HRID 1208341 reaction equation
[CH3:65][N:66]([CH3:67])[CH2:68][CH2:69][CH2:70][N:71]=[C:72]=[N:73][CH2:74][CH3:75].[CH:1]1([c:7]2[c:8]3[cH:9][cH:10][c:11]([C:39](=[O:40])[OH:41])[cH:12][c:13]3[n:14]3[c:15]2-[c:16]2[c:17]([cH:35][cH:36][cH:37][cH:38]2)[CH:18]=[C:19]([C:21](=[O:22])[N:23]2[CH2:24][CH2:25][CH:26]([N:29]4[CH2:30][CH2:31][O:32][CH2:33][CH2:34]4)[CH2:27][CH2:28]2)[CH2:20]3)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[CH:42]([N:43]([CH2:44][CH3:45])[CH:46]([CH3:47])[CH3:48])([CH3:49])[CH3:50].[Cl:86][CH2:87][Cl:88].[ClH:51].[ClH:52].[ClH:64].[NH2:53][CH2:54][c:55]1[n:56][c:57]2[n:58]([cH:59][cH:60][cH:61][cH:62]2)[cH:63]1.[OH:76][n:77]1[c:78]2[cH:79][cH:80][cH:81][cH:82][c:83]2[n:84][n:85]1>>[CH:1]1([c:7]2[c:8]3[cH:9][cH:10][c:11]([C:39](=[O:40])[NH:53][CH2:54][c:55]4[n:56][c:57]5[n:58]([cH:59][cH:60][cH:61][cH:62]5)[cH:63]4)[cH:12][c:13]3[n:14]3[c:15]2-[c:16]2[c:17]([cH:35][cH:36][cH:37][cH:38]2)[CH:18]=[C:19]([C:21](=[O:22])[N:23]2[CH2:24][CH2:25][CH:26]([N:29]4[CH2:30][CH2:31][O:32][CH2:33][CH2:34]4)[CH2:27][CH2:28]2)[CH2:20]3)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

8

Reactant 7

HCID 313Hydrochloric Acid3×HCID 6344DichloromethaneHCID 159081-Ethyl-3-(3'-dimethylaminopropyl)carbodiimideHCID 757711-HydroxybenzotriazoleHCID 81531DiisopropylethylamineHCID 2771121HCID 2771121, compoundHCID 5752668313-cyclohexyl-6-[[4-(4-morpholinyl)-1-piperidinyl]carbonyl]-7H-indolo[2,1-a][2]benzazepine-10-carboxylic acid

Product 1

HCID 1666716713-cyclohexyl-N-(imidazo[1,2-a]pyridin-2-ylmethyl)-6-[[4-(4-morpholinyl)-1-piperidinyl]carbonyl]-7H-indolo[2,1-a][2]benzazepine-10-carboxamide

Sources & evidence

ORD record
ord-ec5efd4e2b1a41c0ad0b0e0a991350bd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

Loading…