Hydroxylamine → Trifluoroacetic acid

HRID 1208448Notes

Reaction equation

HRID 1208448 reaction equation
[CH2:1]([O:2][C:4]([C:5]([CH:6]([c:7]1[cH:8][cH:9][c:10]([O:13][CH2:14][c:15]2[cH:16][c:17]([CH3:25])[n:18][c:19]3[cH:20][cH:21][cH:22][cH:23][c:24]23)[cH:11][cH:12]1)[OH:26])([CH3:27])[CH3:28])=[O:29])[CH3:3].[CH2:43]1[O:44][CH2:45][CH2:46][CH2:47]1.[CH3:34][OH:35].[F:36][C:37]([C:38](=[O:39])[OH:40])([F:41])[F:42].[K+:31].[NH2:32][OH:33].[OH-:30]>>[C:4]([C:5]([CH:6]([c:7]1[cH:8][cH:9][c:10]([O:13][CH2:14][c:15]2[cH:16][c:17]([CH3:25])[n:18][c:19]3[cH:20][cH:21][cH:22][cH:23][c:24]23)[cH:11][cH:12]1)[OH:26])([CH3:27])[CH3:28])(=[O:29])[NH:32][OH:30].[F:36][C:37]([C:38](=[O:39])[OH:40])([F:41])[F:42]

Participants

9

Reactant 7

HCID 787HydroxylamineHCID 813Potassium CationHCID 887MethanolHCID 961HydroxideHCID 6422Trifluoroacetic acidHCID 8028TetrahydrofuranHCID 695964293-Hydroxy-2,2-dimethyl-3-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-propionic acid ethyl ester

Product 2

HCID 6422Trifluoroacetic acidHCID 98428493,N-Dihydroxy-2,2-dimethyl-3-[4-(2-methyl-quinolin-4-ylmethoxy)-phenyl]-propionamide

Sources & evidence

ORD record
ord-185c849ae1f4418bb3f6dbe7b6f99fac
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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