4-Hydroxybenzaldehyde → tert-Butyl 4-(4-formylphenoxy)piperidine-1-carboxylate

HRID 1210467Notes

Reaction equation

HRID 1210467 reaction equation
[C:10]([CH3:11])([CH3:12])([CH3:13])[O:14][C:15](=[O:16])[N:17]1[CH2:18][CH2:19][CH:20]([OH:23])[CH2:21][CH2:22]1.[C:24]([O:25][CH2:26][CH3:27])(=[O:28])[CH3:29].[CH3:30][CH2:31][CH2:32][CH2:33][CH2:34][CH3:35].[O:36]1[CH2:37][CH2:38][CH2:39][CH2:40]1.[OH:1][c:2]1[cH:3][cH:4][c:5]([CH:6]=[O:7])[cH:8][cH:9]1>>[O:1]([c:2]1[cH:3][cH:4][c:5]([CH:6]=[O:7])[cH:8][cH:9]1)[CH:20]1[CH2:19][CH2:18][N:17]([C:15]([O:14][C:10]([CH3:11])([CH3:12])[CH3:13])=[O:16])[CH2:22][CH2:21]1

Participants

6

Reactant 5

HCID 1264-HydroxybenzaldehydeHCID 8028TetrahydrofuranHCID 8058HexaneHCID 8857Ethyl AcetateHCID 643502Tert-butyl 4-hydroxypiperidine-1-carboxylate

Product 1

HCID 22632605tert-Butyl 4-(4-formylphenoxy)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-c90b2a770af94baea94e9fb13e0e25fa
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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