Acetone → 2-Amino-6-({[2-(4-chlorophenyl)-1,3-thiazol-4-yl]methyl}sulfanyl)-4-piperidin-1-ylpyridine-3,5-dicarbonitrile
Reaction equation
[CH2:28]1[CH2:29][CH2:30][NH:31][CH2:32][CH2:33]1.[CH3:36][CH2:37][O:38][C:39](=[O:40])[CH3:41].[CH3:42][C:43](=[O:44])[CH3:45].[Cl-:34].[NH2:1][c:2]1[n:3][c:4]([S:14][CH2:15][c:16]2[n:17][c:18](-[c:21]3[cH:22][cH:23][c:24]([Cl:27])[cH:25][cH:26]3)[s:19][cH:20]2)[c:5]([C:12]#[N:13])[c:6]([S:10][CH3:11])[c:7]1[C:8]#[N:9].[NH4+:35]>>[NH2:1][c:2]1[n:3][c:4]([S:14][CH2:15][c:16]2[n:17][c:18](-[c:21]3[cH:22][cH:23][c:24]([Cl:27])[cH:25][cH:26]3)[s:19][cH:20]2)[c:5]([C:12]#[N:13])[c:6]([N:31]2[CH2:30][CH2:29][CH2:28][CH2:33][CH2:32]2)[c:7]1[C:8]#[N:9]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-f3c4f58d45f04ce4bd2f08101c346693
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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