Potassium Cation → 1-(5-Propylpyrimidin-2-yl)piperidin-4-ol

HRID 1212663Notes

Reaction equation

HRID 1212663 reaction equation
[C:18](=[O:19])([O-:20])[O-:21].[CH3:29][CH2:30][O:31][C:32]([CH3:33])=[O:34].[Cl:8][c:9]1[n:10][cH:11][c:12]([CH2:15][CH2:16][CH3:17])[cH:13][n:14]1.[K+:22].[K+:23].[NH:1]1[CH2:2][CH2:3][CH:4]([OH:7])[CH2:5][CH2:6]1.[O:24]=[CH:25][N:26]([CH3:27])[CH3:28]>>[N:1]1([c:9]2[n:10][cH:11][c:12]([CH2:15][CH2:16][CH3:17])[cH:13][n:14]2)[CH2:2][CH2:3][CH:4]([OH:7])[CH2:5][CH2:6]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 79341Piperidin-4-olHCID 27357842-Chloro-5-propylpyrimidine

Product 1

HCID 670724781-(5-Propylpyrimidin-2-yl)piperidin-4-ol

Sources & evidence

ORD record
ord-ae86109acc9949ae824fa22f75b834d4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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