Isopropanol → 2-methyl-N-(2-(2-morpholinoethylamino)pyrimidin-5-yl)-5-nitrobenzamide

HRID 1212761Notes

Reaction equation

HRID 1212761 reaction equation
[CH:30]([N:31]([CH2:32][CH3:33])[CH:34]([CH3:35])[CH3:36])([CH3:37])[CH3:38].[CH:39]([OH:40])([CH3:41])[CH3:42].[I:1][c:2]1[n:3][cH:4][c:5]([NH:8][C:9]([c:10]2[c:11]([CH3:19])[cH:12][cH:13][c:14]([N+:16](=[O:17])[O-:18])[cH:15]2)=[O:20])[cH:6][n:7]1.[O:21]1[CH2:22][CH2:23][N:24]([CH2:27][CH2:28][NH2:29])[CH2:25][CH2:26]1>>[c:2]1([NH:29][CH2:28][CH2:27][N:24]2[CH2:23][CH2:22][O:21][CH2:26][CH2:25]2)[n:3][cH:4][c:5]([NH:8][C:9]([c:10]2[c:11]([CH3:19])[cH:12][cH:13][c:14]([N+:16](=[O:17])[O-:18])[cH:15]2)=[O:20])[cH:6][n:7]1

Participants

5

Reactant 4

HCID 3776IsopropanolHCID 81531DiisopropylethylamineHCID 4082852-MorpholinoethylamineHCID 24823735N-(2-iodopyrimidin-5-yl)-2-methyl-5-nitrobenzamide

Product 1

HCID 248239022-methyl-N-(2-(2-morpholinoethylamino)pyrimidin-5-yl)-5-nitrobenzamide

Sources & evidence

ORD record
ord-84d72e19a1b644de800f0edd4cf82265
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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