Dimethylformamide → HCID 21897310, compound

HRID 1214338Notes

Reaction equation

HRID 1214338 reaction equation
[Br:1][c:2]1[n:3][cH:4][c:5]([NH:8][C:9]([CH:10]([CH2:11][CH:12]2[CH2:13][CH2:14][CH2:15][CH2:16]2)[c:17]2[cH:18][c:19]([Cl:27])[c:20]([S:23](=[O:24])(=[O:25])[CH3:26])[cH:21][cH:22]2)=[O:28])[n:6][cH:7]1.[CH3:50][N:51]([CH3:52])[CH:53]=[O:54].[Cu:132][I:133].[K:29][C:30]#[N:31].[O:32]1[CH2:33][CH2:34][O:35][CH2:36][CH2:37][O:38][CH2:39][CH2:40][O:41][CH2:42][CH2:43][O:44][CH2:45][CH2:46][O:47][CH2:48][CH2:49]1.[cH:55]1[cH:56][cH:57][c:58]([P:59]([Pd:60]([P:61]([c:62]2[cH:63][cH:64][cH:65][cH:66][cH:67]2)([c:68]2[cH:69][cH:70][cH:71][cH:72][cH:73]2)[c:74]2[cH:75][cH:76][cH:77][cH:78][cH:79]2)([P:80]([c:81]2[cH:82][cH:83][cH:84][cH:85][cH:86]2)([c:87]2[cH:88][cH:89][cH:90][cH:91][cH:92]2)[c:93]2[cH:94][cH:95][cH:96][cH:97][cH:98]2)[P:99]([c:100]2[cH:101][cH:102][cH:103][cH:104][cH:105]2)([c:106]2[cH:107][cH:108][cH:109][cH:110][cH:111]2)[c:112]2[cH:113][cH:114][cH:115][cH:116][cH:117]2)([c:118]2[cH:119][cH:120][cH:121][cH:122][cH:123]2)[c:124]2[cH:125][cH:126][cH:127][cH:128][cH:129]2)[cH:130][cH:131]1>>[c:2]1([C:30]#[N:31])[n:3][cH:4][c:5]([NH:8][C:9]([CH:10]([CH2:11][CH:12]2[CH2:13][CH2:14][CH2:15][CH2:16]2)[c:17]2[cH:18][c:19]([Cl:27])[c:20]([S:23](=[O:24])(=[O:25])[CH3:26])[cH:21][cH:22]2)=[O:28])[n:6][cH:7]1

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 2855718-Crown-6HCID 21897386N-(5-bromo-pyrazin-2-yl)-2-(3-chloro-4-methanesulfonyl-phenyl)-3-cyclopentyl-propionamideHCID 178420554HCID 178420554, compoundHCID 178511842HCID 178511842, compound

Product 1

HCID 21897310HCID 21897310, compound

Sources & evidence

ORD record
ord-ef47f95b6bed4a3fbc2ae93daa23e778
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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