Water → 2-[2-Chloro-6-(4-chloro-benzyl)-pyrimidin-4-yl]-propan-2-ol

HRID 1214443Notes

Reaction equation

HRID 1214443 reaction equation
[CH3:41][CH2:42][O:43][C:44](=[O:45])[CH3:46].[Cl:1][c:2]1[n:3][c:4]([C:16]([CH3:17])([O:18][Si:19]([CH3:20])([CH3:21])[CH3:22])[CH3:23])[cH:5][c:6]([CH2:8][c:9]2[cH:10][cH:11][c:12]([Cl:15])[cH:13][cH:14]2)[n:7]1.[O:36]1[CH2:37][CH2:38][CH2:39][CH2:40]1.[OH2:24].[c:25]1([CH3:26])[cH:27][cH:28][c:29]([S:30]([OH:31])(=[O:32])=[O:33])[cH:34][cH:35]1>>[Cl:1][c:2]1[n:3][c:4]([C:16]([CH3:17])([OH:18])[CH3:23])[cH:5][c:6]([CH2:8][c:9]2[cH:10][cH:11][c:12]([Cl:15])[cH:13][cH:14]2)[n:7]1

Participants

6

Reactant 5

HCID 962WaterHCID 6101p-Toluenesulfonic acidHCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 866567032-Chloro-4-(4-chloro-benzyl)-6-(1-methyl-1-trimethylsilanyloxy-ethyl)-pyrimidine

Product 1

HCID 866567012-[2-Chloro-6-(4-chloro-benzyl)-pyrimidin-4-yl]-propan-2-ol

Sources & evidence

ORD record
ord-513796a8ecbb4aca82f9f7d68181501d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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