Chloride → 4-(2-Fluoropyridin-3-YL)tetrahydro-2H-pyran-4-OL
Reaction equation
[Br:1][c:2]1[c:3]([F:8])[n:4][cH:5][cH:6][cH:7]1.[CH2:21]1[O:22][CH2:23][CH2:24][CH2:25]1.[CH:10]([Mg+:11])([CH3:12])[CH3:13].[Cl-:9].[O:14]1[CH2:15][CH2:16][C:17](=[O:20])[CH2:18][CH2:19]1>>[c:2]1([C:17]2([OH:20])[CH2:16][CH2:15][O:14][CH2:19][CH2:18]2)[c:3]([F:8])[n:4][cH:5][cH:6][cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-37e9de80afc24a29a202d4f791110727
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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