Dimethylformamide → 1-[[4-[8-Chloro-2-(4-isopropylthiazol-2-yl)-7-methoxyquinolin-4-yloxy]-1-(2,2-dimethylnon-8-enoyl)pyrrolidine-2-carbonyl]amino]-2-vinylcyclopropanecarboxylic acid ethyl ester
Reaction equation
[CH2:20]([CH3:21])[O:22][C:23](=[O:24])[C:25]1([NH:30][C:31](=[O:32])[CH:33]2[NH:34][CH2:35][CH:36]([O:38][c:39]3[cH:40][c:41](-[c:52]4[s:53][cH:54][c:55]([CH:57]([CH3:58])[CH3:59])[n:56]4)[n:42][c:43]4[c:44]([Cl:51])[c:45]([O:49][CH3:50])[cH:46][cH:47][c:48]34)[CH2:37]2)[CH:26]([CH:28]=[CH2:29])[CH2:27]1.[CH3:1][C:2]([C:3](=[O:4])[OH:5])([CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH:11]=[CH2:12])[CH3:13].[CH3:60][CH2:61][N:62]([CH2:63][CH3:64])[CH2:65][CH3:66].[Cl:14][C:15]([C:16]([Cl:17])=[O:18])=[O:19].[Cl:67][CH2:68][Cl:69].[O:70]=[CH:71][N:72]([CH3:73])[CH3:74]>>[CH3:1][C:2]([C:3](=[O:5])[N:34]1[CH:33]([C:31]([NH:30][C:25]2([C:23]([O:22][CH2:20][CH3:21])=[O:24])[CH:26]([CH:28]=[CH2:29])[CH2:27]2)=[O:32])[CH2:37][CH:36]([O:38][c:39]2[cH:40][c:41](-[c:52]3[s:53][cH:54][c:55]([CH:57]([CH3:58])[CH3:59])[n:56]3)[n:42][c:43]3[c:44]([Cl:51])[c:45]([O:49][CH3:50])[cH:46][cH:47][c:48]23)[CH2:35]1)([CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH:11]=[CH2:12])[CH3:13]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-7b7b16fd11dc48759527ec41ef0fc217
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…