Dimethylformamide → racemic (2'R,3R,4'S)-6-chloro-4'-(3-chlorophenyl)-1'-ethyl-2,3-dihydro-2'-(2-methylphenyl)-2,6'-dioxo spiro[indole-3,3'-piperidine]-1-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[C:9](=[O:38])[C:10]2([c:11]3[cH:12][cH:13][c:14]([Cl:17])[cH:15][c:16]31)[CH:18]([c:31]1[c:32]([CH3:37])[cH:33][cH:34][cH:35][cH:36]1)[NH:19][C:20](=[O:30])[CH2:21][CH:22]2[c:23]1[cH:24][c:25]([Cl:29])[cH:26][cH:27][cH:28]1.[CH3:44][N:45]([CH3:46])[CH:47]=[O:48].[H-:39].[I:41][CH2:42][CH3:43].[Li+:40]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[C:9](=[O:38])[C:10]2([c:11]3[cH:12][cH:13][c:14]([Cl:17])[cH:15][c:16]31)[CH:18]([c:31]1[c:32]([CH3:37])[cH:33][cH:34][cH:35][cH:36]1)[N:19]([CH2:42][CH3:43])[C:20](=[O:30])[CH2:21][CH:22]2[c:23]1[cH:24][c:25]([Cl:29])[cH:26][cH:27][cH:28]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-5fc01f5f951a4d72925e489fc3e55734
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
Loading…