Tetrahydrofuran → Tert-butyl 1-(cyclopropylsulfonylcarbamoyl)-2-(difluoromethyl)cyclopropylcarbamate
Reaction equation
[C:18]([n:19]1[cH:20][cH:21][n:22][cH:23]1)([n:24]1[cH:25][cH:26][n:27][cH:28]1)=[O:29].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][C:9]1([C:15](=[O:16])[OH:17])[CH:10]([CH:12]([F:13])[F:14])[CH2:11]1.[CH2:37]1[CH2:38][CH2:39][C:40]2=[N:45][CH2:44][CH2:43][CH2:42][N:41]2[CH2:46][CH2:47]1.[CH:30]1([S:33](=[O:34])(=[O:35])[NH2:36])[CH2:31][CH2:32]1.[O:48]1[CH2:49][CH2:50][CH2:51][CH2:52]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][C:9]1([C:15](=[O:17])[NH:36][S:33]([CH:30]2[CH2:31][CH2:32]2)(=[O:34])=[O:35])[CH:10]([CH:12]([F:13])[F:14])[CH2:11]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-6eab6c66888342d39b8d08359669b7e4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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