Phthalimide → 2-[4-(4-Chlorophenyl)but-3-yn-2-yl]-1H-isoindole-1,3(2H)-dione

HRID 1220583Notes

Reaction equation

HRID 1220583 reaction equation
[CH2:55]1[O:56][CH2:57][CH2:58][CH2:59]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:8]#[C:9][CH:10]([CH3:11])[OH:12])[cH:6][cH:7]1.[O:13]=[C:14]1[NH:15][C:16](=[O:17])[c:18]2[cH:19][cH:20][cH:21][cH:22][c:23]21.[O:43]=[C:44]([O:45][CH2:46][CH3:47])[N:48]=[N:49][C:50]([O:51][CH2:52][CH3:53])=[O:54].[c:24]1([P:25]([c:26]2[cH:27][cH:28][cH:29][cH:30][cH:31]2)[c:32]2[cH:33][cH:34][cH:35][cH:36][cH:37]2)[cH:38][cH:39][cH:40][cH:41][cH:42]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:8]#[C:9][CH:10]([CH3:11])[N:15]2[C:14](=[O:13])[c:23]3[c:18]([cH:19][cH:20][cH:21][cH:22]3)[C:16]2=[O:17])[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 6809PhthalimideHCID 8028TetrahydrofuranHCID 11776TriphenylphosphineHCID 220568ethyl N-ethoxycarbonyliminocarbamateHCID 23006387HCID 23006387, compound

Product 1

HCID 573568212-[4-(4-Chlorophenyl)but-3-yn-2-yl]-1H-isoindole-1,3(2H)-dione

Sources & evidence

ORD record
ord-3ddeda3e1381404891c0a5355fcfcdd5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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