Tetrahydrofuran → (4-Cyclohexyl-3-oxo-butyl)-methyl-carbamic acid tert-butyl ester

HRID 1222227Notes

Reaction equation

[Br:1][CH2:2][CH:3]1[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8]1.[C:11]([CH3:12])([CH3:13])([CH3:14])[O:15][C:16]([N:17]([CH3:18])[CH2:19][CH2:20][C:21]([N:22]([O:23][CH3:24])[CH3:25])=[O:26])=[O:27].[I:10].[Mg:9].[O:28]1[CH2:29][CH2:30][CH2:31][CH2:32]1>>[CH2:2]([CH:3]1[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8]1)[C:21]([CH2:20][CH2:19][N:17]([C:16]([O:15][C:11]([CH3:12])([CH3:13])[CH3:14])=[O:27])[CH3:18])=[O:26]

Participants

Reactant 5

HCID 8028Tetrahydrofuran

HCID 24841Hydrogen iodide

HCID 137636Cyclohexane, (bromomethyl)-

HCID 5462224Magnesium

HCID 59364357Tert-butyl 3-(methoxy(methyl)amino)-3-oxopropyl(methyl)carbamate

Product 1

HCID 59769551(4-Cyclohexyl-3-oxo-butyl)-methyl-carbamic acid tert-butyl ester

Sources & evidence

ORD record: ord-430af8262f6948ca874173908d5925fb
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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