Chloride → 2,4-Diamino-6-methyl-5-[3-(4-chlorophenyl)-3-methyl-1-butenyl]pyrimidine

HRID 122237Notes

Reaction equation

HRID 122237 reaction equation
[CH3:1][C:2]([CH:3]=[CH:4][Sn:5]([CH3:6])([CH3:7])[CH3:8])([CH3:9])[c:10]1[cH:11][cH:12][c:13]([Cl:16])[cH:14][cH:15]1.[CH3:29][c:30]1[cH:31][c:32]([C:33]([CH3:34])([CH3:35])[CH3:36])[c:37]([OH:38])[c:39]([C:40]([CH3:41])([CH3:42])[CH3:43])[cH:44]1.[CH3:45][N:46]([CH3:47])[CH:48]=[O:49].[Cl-:28].[Li+:27].[NH2:17][c:18]1[n:19][c:20]([CH3:26])[c:21]([I:25])[c:22]([NH2:24])[n:23]1>>[CH3:1][C:2]([CH:3]=[CH:4][c:21]1[c:20]([CH3:26])[n:19][c:18]([NH2:17])[n:23][c:22]1[NH2:24])([CH3:9])[c:10]1[cH:11][cH:12][c:13]([Cl:16])[cH:14][cH:15]1

Participants

7

Reactant 6

HCID 312ChlorideHCID 6228DimethylformamideHCID 28486Lithium ionHCID 314042,6-Di-tert-butyl-4-methylphenolHCID 158557925-Iodo-6-methylpyrimidine-2,4-diamineHCID 676329003-Methyl-3-(4-chlorophenyl)-1-trimethylstannyl-1-butene

Product 1

HCID 12148412,4-Diamino-6-methyl-5-[3-(4-chlorophenyl)-3-methyl-1-butenyl]pyrimidine

Sources & evidence

ORD record
ord-920dd3aa6c2a4dd6aa3d173f80c6702e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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