HRID1224513

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6809

Phthalimide

C8H5NO2

HCID8028

Tetrahydrofuran

C4H8O

HCID11776

Triphenylphosphine

C18H15P

HCID75555

未命名化合物

HCID22248400

tert-Butyl 4-fluoro-4-(hydroxymethyl)piperidine-1-carboxylate

C11H20FNO3

PRODUCTS

生成物

结构：CC(C)(C)OC(=O)N1CCC(F)(CN2C(=O)c3ccccc3C2=O)CC1

HCID53415317

tert-Butyl 4-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]-4-fluoropiperidine-1-carboxylate

C19H23FN2O4

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-a1a8711bf1bb43e7b5cfe8317d3b59c2
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (5/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (5/10)

反应 SMILES

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([CH2:14][OH:15])([F:16])[CH2:12][CH2:13]1.[CH2:61]1[O:62][CH2:63][CH2:64][CH2:65]1.[O:36]=[C:37]([O:38][CH:39]([CH3:40])[CH3:41])[N:42]=[N:43][C:44]([O:45][CH:46]([CH3:47])[CH3:48])=[O:49].[O:50]=[C:51]1[NH:52][C:53](=[O:54])[c:55]2[cH:56][cH:57][cH:58][cH:59][c:60]21.[c:17]1([P:18]([c:19]2[cH:20][cH:21][cH:22][cH:23][cH:24]2)[c:25]2[cH:26][cH:27][cH:28][cH:29][cH:30]2)[cH:31][cH:32][cH:33][cH:34][cH:35]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][C:11]([CH2:14][N:52]2[C:51](=[O:50])[c:60]3[c:55]([cH:56][cH:57][cH:58][cH:59]3)[C:53]2=[O:54])([F:16])[CH2:12][CH2:13]1