Dimethylformamide → 2-chloro-6-fluoro-N-(3-methoxy-1H-pyrazolo[3,4-b]pyridin-5-yl)-3-(propylsulfonamido)benzamide
Reaction equation
[CH3:19][O:20][c:21]1[n:22][nH:23][c:24]2[n:25][cH:26][c:27]([NH2:30])[cH:28][c:29]12.[CH3:31][CH2:32][N:33]=[C:34]=[N:35][CH2:36][CH2:37][CH2:38][N:39]([CH3:40])[CH3:41].[CH3:52][N:53]([CH3:54])[CH:55]=[O:56].[CH3:57][CH2:58][O:59][C:60](=[O:61])[CH3:62].[Cl:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[c:7]([F:18])[cH:8][cH:9][c:10]1[NH:11][S:12](=[O:13])(=[O:14])[CH2:15][CH2:16][CH3:17].[OH:42][n:43]1[c:44]2[c:45]([cH:46][cH:47][cH:48][cH:49]2)[n:50][n:51]1>>[Cl:1][c:2]1[c:3]([C:4](=[O:6])[NH:30][c:27]2[cH:26][n:25][c:24]3[nH:23][n:22][c:21]([O:20][CH3:19])[c:29]3[cH:28]2)[c:7]([F:18])[cH:8][cH:9][c:10]1[NH:11][S:12](=[O:13])(=[O:14])[CH2:15][CH2:16][CH3:17]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-fcf6c767d8024180913eb8abd3ff34fb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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