1-Methylpyrrolidine-2-carboxylic acid → (6-methoxy-7-nitro-3,4-dihydro-2H-quinolin-1-yl)-(1-methylpyrrolidin-2-yl)methanone

HRID 1226571Notes

Reaction equation

HRID 1226571 reaction equation
[CH3:16][N:17]1[CH:18]([C:19](=[O:20])[OH:21])[CH2:22][CH2:23][CH2:24]1.[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:10]([cH:11][c:12]1[N+:13](=[O:14])[O-:15])[NH:9][CH2:8][CH2:7][CH2:6]2.[CH3:58][N:59]([CH3:60])[CH:61]=[O:62].[CH3:63][CH2:64][O:65][C:66](=[O:67])[CH3:68].[CH:49]([N:50]([CH2:51][CH3:52])[CH:53]([CH3:54])[CH3:55])([CH3:56])[CH3:57].[P-:25]([F:26])([F:27])([F:28])([F:29])([F:30])[F:31].[n:32]1([O:33][C:34]([N:35]([CH3:36])[CH3:37])=[N+:38]([CH3:39])[CH3:40])[c:41]2[n:42][cH:43][cH:44][cH:45][c:46]2[n:47][n:48]1>>[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:10]([cH:11][c:12]1[N+:13](=[O:14])[O-:15])[N:9]([C:19]([CH:18]1[N:17]([CH3:16])[CH2:24][CH2:23][CH2:22]1)=[O:20])[CH2:8][CH2:7][CH2:6]2

Participants

8

Reactant 7

HCID 5571-Methylpyrrolidine-2-carboxylic acidHCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 9886HexafluorophosphateHCID 81531DiisopropylethylamineHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 59441908HCID 59441908, compound

Product 1

HCID 178486490(6-methoxy-7-nitro-3,4-dihydro-2H-quinolin-1-yl)-(1-methylpyrrolidin-2-yl)methanone

Sources & evidence

ORD record
ord-620ceb4e0ea14137880d78415b0190e2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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