Tetrahydrofuran → 2-(6-fluoro-2-hydroxy-1-propan-2-yl-3,4-dihydro-1H-naphthalen-2-yl)-N,N-dimethylacetamide
Reaction equation
[CH3:9][N:10]([C:11]([CH3:12])=[O:13])[CH3:14].[CH:1]([N-:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7].[F:15][c:16]1[cH:17][c:18]2[c:23]([cH:24][cH:25]1)[CH:22]([CH:26]([CH3:27])[CH3:28])[C:21](=[O:29])[CH2:20][CH2:19]2.[Li+:8].[O:30]1[CH2:31][CH2:32][CH2:33][CH2:34]1>>[CH3:9][N:10]([C:11]([CH2:12][C:21]1([OH:29])[CH2:20][CH2:19][c:18]2[cH:17][c:16]([F:15])[cH:25][cH:24][c:23]2[CH:22]1[CH:26]([CH3:27])[CH3:28])=[O:13])[CH3:14]Participants
6
Sources & evidence
- ORD record
- ord-8e231f031f604907a3d0179d93f945b9
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…