Phthalimide → 2-[3-(1-Diphenylmethylpiperidine-4-yl)-propyl]-isoindol-1,3-dione

HRID 1229375Notes

Reaction equation

HRID 1229375 reaction equation
[CH2:54]1[O:55][CH2:56][CH2:57][CH2:58]1.[O:43]=[C:44]1[NH:45][C:46](=[O:47])[c:48]2[cH:49][cH:50][cH:51][cH:52][c:53]21.[c:1]1([CH:7]([N:8]2[CH2:9][CH2:10][CH:11]([CH2:14][CH2:15][CH2:16][OH:17])[CH2:12][CH2:13]2)[c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1.[c:24]1([P:25]([c:26]2[cH:27][cH:28][cH:29][cH:30][cH:31]2)[c:32]2[cH:33][cH:34][cH:35][cH:36][cH:37]2)[cH:38][cH:39][cH:40][cH:41][cH:42]1>>[c:1]1([CH:7]([N:8]2[CH2:9][CH2:10][CH:11]([CH2:14][CH2:15][CH2:16][N:45]3[C:44](=[O:43])[c:53]4[c:48]([cH:49][cH:50][cH:51][cH:52]4)[C:46]3=[O:47])[CH2:12][CH2:13]2)[c:18]2[cH:19][cH:20][cH:21][cH:22][cH:23]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

5

Reactant 4

HCID 6809PhthalimideHCID 8028TetrahydrofuranHCID 11776TriphenylphosphineHCID 18425709HCID 18425709, compound

Product 1

HCID 184257262-[3-(1-Diphenylmethylpiperidine-4-yl)-propyl]-isoindol-1,3-dione

Sources & evidence

ORD record
ord-211fccd40d064e89a99e08cc565fe0b7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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