Sodium ion → Tert-butyl 4-(hydroxymethyl)piperidine-1-carboxylate

HRID 1229658Notes

Reaction equation

HRID 1229658 reaction equation
[Al+3:20].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([C:12](=[O:13])[O:14][CH2:15][CH3:16])[CH2:17][CH2:18]1.[H-:19].[H-:22].[H-:23].[H-:24].[Li+:21].[Na+:40].[Na+:41].[O:42]1[CH2:43][CH2:44][CH2:45][CH2:46]1.[OH2:25].[OH2:26].[OH2:27].[OH2:28].[OH2:29].[OH2:30].[OH2:31].[OH2:32].[OH2:33].[OH2:34].[S:35]([O-:36])([O-:37])(=[O:38])=[O:39]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([CH2:12][OH:13])[CH2:17][CH2:18]1

Participants

9

Reactant 8

HCID 923Sodium ion2×HCID 962Water10×HCID 1117Sulfate IonHCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 27588121-Tert-butyl 4-ethyl piperidine-1,4-dicarboxylate

Product 1

HCID 2764081Tert-butyl 4-(hydroxymethyl)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-aed9a819358e4a98841061c24fd306cd
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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