Tetrahydrofuran → 7-Chloro-3-hydroxymethyl-2-methylimidazo[2,1-a]isoquinoline
Reaction equation
[Al+3:2].[CH3:27][CH2:28][O:29][C:30](=[O:31])[CH3:32].[Cl:7][c:8]1[c:9]2[cH:10][cH:11][n:12]3[c:13]([c:14]2[cH:15][cH:16][cH:17]1)[n:18][c:19]([CH3:26])[c:20]3[C:21](=[O:22])[O:23][CH2:24][CH3:25].[H-:1].[H-:4].[H-:5].[H-:6].[Li+:3].[O:33]1[CH2:34][CH2:35][CH2:36][CH2:37]1>>[Cl:7][c:8]1[c:9]2[cH:10][cH:11][n:12]3[c:13]([c:14]2[cH:15][cH:16][cH:17]1)[n:18][c:19]([CH3:26])[c:20]3[CH2:21][OH:22]Participants
7
Sources & evidence
- ORD record
- ord-4e7c2e88cd634830bc26e596fe60fbae
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (5/10)
Reaction notes
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