Hydrochloric Acid → (+)-1-(4-Phenyl-2,3-dihydro-1-benzofuran-2-yl)methanamine

HRID 1230113Notes

Reaction equation

HRID 1230113 reaction equation
[CH3:1][c:2]1[cH:3][cH:4][c:5]([S:6]([O:7][CH2:8][CH:9]2[CH2:10][c:11]3[c:12](-[c:13]4[cH:14][cH:15][cH:16][cH:17][cH:18]4)[cH:19][cH:20][cH:21][c:22]3[O:23]2)(=[O:24])=[O:25])[cH:26][cH:27]1.[CH3:55][CH2:56][OH:57].[CH:58]([OH:59])([CH3:60])[CH3:61].[ClH:54].[N-:29]=[N+:30]=[N-:31].[N-:51]=[N+:52]=[N-:53].[Na+:28].[c:32]1(-[c:38]2[cH:39][cH:40][cH:41][c:42]3[c:43]2[CH2:44][CH:45]([CH2:47][N:48]=[N+:49]=[N-:50])[O:46]3)[cH:33][cH:34][cH:35][cH:36][cH:37]1>>[c:32]1(-[c:38]2[cH:39][cH:40][cH:41][c:42]3[c:43]2[CH2:44][CH:45]([CH2:47][NH2:48])[O:46]3)[cH:33][cH:34][cH:35][cH:36][cH:37]1

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 702EthanolHCID 923Sodium ionHCID 3776IsopropanolHCID 33558Azide2×HCID 86599074(+/-)-(4-Phenyl-2,3-dihydro-1-benzofuran-2-yl)methyl 4-methylbenzenesulfonateHCID 86599170(+/-)-(4-Phenyl-2,3-dihydro-1-benzofuran-2-yl)methyl azide

Product 1

HCID 16226460(+)-1-(4-Phenyl-2,3-dihydro-1-benzofuran-2-yl)methanamine

Sources & evidence

ORD record
ord-9cd29575fb1446aabbbfacb0a3cf4f29
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (5/10)

Reaction notes

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